This sophisticated technology of carbohydrate synthesis revolutionizes the field of TACA research and allows us to access not only single molecules, but whole classes of TACAs and other related cell surface glycans for translation of our comprehensive knowledge of immunology and oncology into novel therapeutic approaches against cancer. Our long-term goal is the improvement of current tumor therapy. We seek to achieve this by exploiting the underlying biology in an optimum way for complete killing of the tumor cells. Therefore, apart from the generation of highly specific binders (e.g. antibodies) their modification to support the killing of the tumor cell to maximum effect using our deep knowledge of the underlying biology is the most prominent goal of Tacalyx.