Tacalyx GmbH located with its laboratories in the center of Berlin is a biopharmaceutical start-up company researching and developing innovative therapeutics targeting tumor-specific carbohydrate antigens (TACAs) for different cancer indications. To strengthen our team we are looking to recruit a

Research Scientist (m/f) Antibody Biology

Your Responsibilities:
We are seeking an enthusiastic, self-motivated and experienced bench-level scientist. The major focus of this position will include developing and executing biological assays for antibody characterization. The position requires a PhD in oncology or immunology with extensive hands-on experience in the setup, optimization and execution of bioanalytical assays and their evaluation and interpretation. Main tasks of this position are:

• Perform in vitro biology experiments to support antibody characterization
• Optimize and implement cellular and biochemical assays using various technology platforms (including flow cytometry, rtPCR, imaging, ELISA) to screen and profile antibody candidates
• Establish and cultivate clinically-relevant primary cell model systems as antibody validation platform
• Execution and analysis of screening experiments in own responsibility
• Keeping up to date with scientific literature, advancements in the field and new technologies relevant to the project

• Ph.D. in oncology or immunology
• Hands-on experience in primary cell culture (e.g. multicellular tumor organoids, spheroids, as well as immune cells) is essential to select clinically-relevant cellular systems for antibody characterization
• Demonstrated expertise in evaluating the effects of antibodies in cells and/or characterizing signaling networks in tumor cells
• Experience in the fields of molecular and cellular biology, protein biochemistry, immunohistochemistry
• Expertise in immunology techniques including multi-color flow cytometry, cytokine analysis, cytotoxicity and proliferation assays
• Ability to quickly adopt new laboratory skills and to work as part of a team
• Expertise to perform and prioritize multiple simultaneous tasks
• Capability to design and execute experiments, critically interpret experimental results, and present data in a meaningful manner
• Excellent communication skills, both in German and English

We offer a competitive salary as well as excellent opportunities for professional and personal development. If you are self-driven, interested to work in a professional and ambitious field and your background and personal experience fits this profile, please send us your complete application to info@tacalyx.com, including a cover letter, your CV and your earliest possible starting date as well as your salary expectation. EU visa and/or working permission is required.